First Baby Born Using Uterus Transplanted From Deceased Donor: Doctors

A medical team in São Paulo with a baby born via a uterine transplant.									Divulgação

A medical team in São Paulo with a baby born via a uterine transplant. Divulgação

A Brazilian woman was the first to give birth after receiving a womb transplant from a deceased donor, Reuters reported.

Infertility affects one in seven people in Britain, and while some problems can be solved through IVF, most women with womb issues have no alternative but adoption or surrogacy.

British expert Andrew Shennan, professor of obstetrics at King's College London, said: "Uterine transplant and subsequent pregnancies, including from live donors, have previously been reported, but this is the first case of a successful pregnancy from a deceased donor".

The mother was born without a uterus and received the transplant in 2016.

However, he cautioned: "Uterine transplantation is a novel technique and should be regarded as experimental".

It said the case involved connecting veins from the donor's uterus with the recipient's veins, as well as linking arteries, ligaments, and vaginal canals.

With this recent success comes not just the promise of greater access to donor organs, but vital information on what a transplanted uterus requires to successfully carry an embryo to full term. "While uterine transplantation sounds extreme, it can be indicated in women born without a uterus, or in women who have a non-functional or surgically-absent uterus".

Since live uterus donors are a limitation, the report shows that uterus transplants from deceased donors are feasible and may open access for all women with uterine problems, without the need for live donors, as is the practice now.

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In the us, around 10 percent of women aged between 15 to 44 struggle with fertility, according to the Centers for Disease Control and Prevention.

In 2016, doctors at the Cleveland Clinic in OH transplanted a uterus from a deceased donor, but it failed after an infection developed.

The female baby was delivered via Caesarean section at a hospital in Sao Paulo, Brazil, in December 2017 when the mother was nearly 36 weeks pregnant, the study said.

"The use of deceased donors could greatly broaden access to this treatment", Dr. Dani Ejzenberg, who led the research, said in a statement.

The current need for live donors "is a major limitation as donors are rare, typically being willing and eligible family members or close friends", Dr Ejzenberg said. "While uterine surrogacy is legal in the US, this offers an option, albeit an extreme and expensive one, to women who want to carry their own baby". Seven months after the transplant, doctors transferred an embryo made via in-vitro fertilization from the woman's egg and her husband's sperm into her womb.

But there are far more women in need of transplants than there are potential live donors, so doctors wanted to find out if the procedure could work using the uterus of a woman who had died.

The first successful live uterus transplant took place in Sweden, in 2014, prompting a rise in uterus transplant programs across the world, wrote the authors of the case study. The baby was born on December 15, 2017, through a C-section, and is believed to be the first to be born with a uterus from a deceased donor.

No. In order to keep the uterus after birth, the mother would have to continue taking immune system suppression medications which can pose risks. At the age of 7 months and 20 days, the baby continued to breastfeed and weighed 15 pounds, 14 ounces. One in 500 women have uterine anomalies due to congenital anomalies, or through unexpected malformation, hysterectomy, or infection.

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